Investigating the impact of symptom propagation on health economic outcomes

In traditional models of infectious diseases, the symptom severity of an infected individual does not impact the symptom severity of those infected by them. However, there is evidence in the literature that an individual’s disease severity may pass on to those they infect, meaning that symptoms propagate with infection. The extent to which a symptom propagation exists and its subsequent impact on health economic outcomes are still relatively unknown.

These avenues of research are being explored as part of Phoebe Asplin’s PhD project at the University of Warwick. The project is being done in collaboration with Matt Keeling (University of Warwick) and Rebecca Mancy (University of Glasgow).

Preprints:

• Symptom propagation in respiratory pathogens of public health concern: a review of the evidence.
  Phoebe Asplin, Rebecca Mancy, Thomas Finnie, Fergus Cumming, Matt J Keeling, Edward M Hill. (2024)
  medRxiv. doi:10.1101/2024.01.05.24300898
  

• Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation.
  Phoebe Asplin, Matt J Keeling, Rebecca Mancy, Edward M Hill. (2023)
  medRxiv. doi:10.1101/2023.07.12.23292544